Associate Scientist I
|Reference # :||18-01804||Title :||Associate Scientist I|
|Location :||Worcester, MA|
|Position Type :||Contract|
|Experience Level :||Start Date / End Date :||10/29/2018 / 04/29/2019|
|We are seeking a highly motivated and dedicated ligand binding assay Associate Scientist to join the DMPK-BA department at Client Bioresearch Center in Worcester, MA.|
The LBA Bioanalytical group at ABC DMPK conducts quantitative bioanalysis assay of large molecule therapeutics like mAb, ADC, fusion protein and bi-specifics for PK, PD and TK studies using ligand binding assays to support drug discovery and early development efforts.
The main responsibilities of the Associate Scientist I include: Sample analysis using ligand binding assay, generate high quality bioanalytical data enable data summary and PK analysis. Sample and reagent management using electronic tools including LIMS.
Duties & Responsibilities:
? Plan and execute experiments based bioanalytical protocol and in vivo study design.
? Analyze pre-clinical in vivo samples based on operational schedule.
? Qualify ligand binding assay based on BA protocol, interpret result and make decision on assay readiness.
? Data archiving in ELN and LIMS.
? Effectively communicate experimental plan, and results orally and in writing. Contribute to technical report writing.
? Sample management in LIMS.
? Write, and update experimental protocols and procedures with supervision.
? Initiate, design, interpret, troubleshoot operational assay independently and efficiently.
? Bachelor's Degree in biology, chemistry or pharmacology.
? 0-2 years of pharmaceutical, biotechnology industry experience.
? Attention to detail.
? Ability to operate and maintain laboratory equipment with independence.
? Experience in automated ligand binding workflow is highly desirable.
? Experience in data driven troubleshooting ligand binding assay is highly desirable.
? Proven problem solving ability.
? Excellent written and verbal communication skills and ability to draft technical reports.
? Proficiency with computers and data analysis software including Excel and LIMS
? Ability and willingness to work effectively in a highly collaborative environment.
What hours and days will this person work on a weekly basis?
40hr/week, 5 days/week.
? What are the top 5 skills/requirements this person is required have?
o a. Required Skill 1: ligand binding assay including ELISA.
o b. Required Skill 2: pipetting, liquid handling
o c. Required Skill 3: Reagent and buffer preparation
o d. Required Skill 4: notebooking
o e. Required Skill 5: Excel
? What years of experience, education, and/or certification is required?
o BS, with 0-2 years of experience.
? What is a nice to have (but not required) regarding skills, requirements, experience, education, or certification?
o Ligand binding method development, LIMS, sample management, liquid handling automation
? What is the environment that this person will be working in (i.e. group setting vs. individual role)?
o Group setting.
Job Status: Contract/Temporary